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Colorful Book Spines

Publications

Book Chapters, Patents, Journals, Conference Abstracts/Proceedings

Book Chapters

Andy K. S. Lau, Terence T. W. Wong, Ho Cheung Shum, Kenneth K. Y. Wong, Kevin K. Tsia, “Ultrafast Microfluidic Cellular Imaging by Optical Time-Stretch,” Imaging Flow Cytometry: Methods and Protocols, (Methods in Molecular Biology), Humana Press Inc. (Nov 2015)

Patents

​       @ HKUST​

  1. Terence. T. W. Wong, Bingxin Huang, Lei Kang, “Deep Learning Enables Smartphone-based Quantitative and Label-Free Imaging for Hematological Analysis,” US provisional patent (No. 63/340,947)

  2. Terence T. W. Wong, Weixing Dai, Ivy H. M. Wong, "Label-free Multi-histochemical Virtual Staining Enabled by Multi-spectral Autofluorescence and Weakly-supervised Learning," US provisional patent (No. 63/254,547)

  3. Terence. T. W. Wong, Wentao Yu, Yan Zhang, Lei Kang, "Translational rapid ultraviolet-excited sectioning tomography assisted with deep learning," US provisional patent (No. 62/254,546)

  4. Terence T. W. Wong, Yan Zhang, Lei Kang, Xiufeng Li, Ivy H. M. Wong, "SLIDE-FREE HISTOLOGICAL IMAGING METHOD AND SYSTEM," (PCT/CN2020/108454)

  5. Terence T. W. Wong, Yan Zhang, Lei Kang, Xiufeng Li, Ivy H. M. Wong, “High-throughput, label-free and slide-free histological imaging by intrinsic optical absorption assisted by deep learning,” US provisional patent (No. 62/973,101) 

    Before HKUST

  6. Kevin K. Tsia, Terence Wong, Andy Lau, Anson Tang, “Apparatus and Method for quantitative phase-gradient chirped-wavelength-encoded optical imaging,” US patent (No. US010365465B2)

  7. Lihong V. Wang, Yang Li, Terence Wong, “Multifocal Photoacoustic Microscopy Through An Ergodic  Relay,” US provisional patent (No. 16/540,936)

Journals

​      @ HKUST​

  1. Lei Kang*, Wentao Yu*, Yan Zhang, and Terence T. W. Wong, "Deep learning enables rapid whole organ virtual hematoxylin and eosin histological imaging with vibratome assisted ultraviolet microscopy," (under preparation) (*The authors contributed equally to the work)

  2. Yan Zhang, Bingxin Huang, Lei Kang, Victor T. C. Tsang, Jiajie Wu, Claudia T. K. Lo, and Terence T. W. Wong, "Label-free and non-destructive histological imaging of human lung adenocarcinomas with ultraviolet single-plane illumination microscopy," (under preparation)

  3. Weixing Dai*, Ivy H. M. Wong*, and Terence T. W. Wong, "A Weakly Supervised Deep Generative Model for Complex Image Restoration and Style Transformation," (under review) (*The authors contributed equally to the work) [preprint from TechRxiv]

  4. Wentao Yu, Lei Kang, Victor T. C. Tsang, Yan Zhang, Ivy H. M. Wong, and Terence T. W. Wong, "Translational rapid ultraviolet-excited sectioning tomography for whole-organ multicolor imaging with real-time molecular staining," eLife 11:e81015 (2022) [Link]

  5. Xiufeng Li, Kylie Yeung, Victor T. C. Tsang, Bingxin Huang, Claudia T. K. Lo, and Terence T. W. Wong, "Low-cost High-resolution Photoacoustic Microscopy of Blood Oxygenation with Two Laser Diodes," Biomed. Opt. Express 13(7), 3893–3903 (2022) [Link]

  6. Xiufeng Li, Lei Kang, Claudia T. K. Lo, Victor T. C. Tsang, and Terence T. W. Wong, "High-speed Ultraviolet Photoacoustic Microscopy for Histological Imaging with Virtual-staining Assisted by Deep Learning," J. Vis. Exp. (182), e63649 (2022) [Link]

  7. Yan Zhang, Lei Kang, Claudia T. K. Lo, and Terence T. W. Wong, "Rapid slide-free and non-destructive histological imaging using wide-field optical-sectioning microscopy," Biomed. Opt. Express 13(5), 2782–2796 (2022) [Link]

  8. Yan Zhang, Bingxin Huang, Jiajie Wu, and Terence T. W. Wong, "Advances in optical microscopy revolutionize the practice of surgical pathology with rapid and non-destructive tissue assessment," Eur. Phys. J. Spec. Top. (2022) (Invited review) [Link]

  9. Yan Zhang, Lei Kang, Wentao Yu, Victor T. C. Tsang, and Terence T. W. Wong, "Three-dimensional label-free histological imaging of whole organs by microtomy-assisted autofluorescence tomography," iScience 25, 103721 (2022) [Link]
          *also featured by FocalPlane [Details]

  10. Ivy H. M. Wong, Yan Zhang, Zhenghui Chen, Lei Kang, and Terence T. W. Wong, "Slide-free Histological Imaging by Microscopy with Ultraviolet Surface Excitation using Speckle Illumination," Photon. Res. 10(1), 01000120 (2022) [Link]

  11. Yan Zhang*, Lei Kang*, Ivy H. M. Wong, Weixing Dai, Xiufeng Li, Ronald C. K. Chan, Michael K. Y. Hsin, and Terence T. W. Wong, "High-throughput, label-free and slide-free histological imaging by computational microscopy and unsupervised learning," Adv. Sci. 9, 2102358 (2022) [Link] (*The authors contributed equally to the work)          
          *also selected as the inside back cover in Advanced Science [Link]

  12. Xiufeng Li*, Jack C. K. Kot*, Victor T. C. Tsang, Claudia T. K. Lo, Bingxin Huang, Ye Tian, Ivy H. M. Wong, Helen H. Y. Cheung, Lei Kang, Atta C. Y. Chang, and Terence T. W. Wong, "Ultraviolet Photoacoustic Microscopy with Tissue Clearing for High-contrast Histological Imaging," Photoacoustics 25, 100313 (2022) [Link] (*The authors contributed equally to the work)

  13. Lei Kang, Xiufeng Li, Yan Zhang, and Terence T. W. Wong, "Deep Learning Enables Ultraviolet Photoacoustic Microscopy Based Histological Imaging With Near Real-time Virtual Staining," Photoacoustics 25, 100308 (2022) [Link]

  14. Zhenghui Chen, Wentao Yu, Ivy H. M. Wong, and Terence T. W. Wong, "Deep-learning-assisted microscopy with ultraviolet surface excitation for rapid slide-free histological imaging," Biomed. Opt. Express 12(9), 5920–5938 (2021) [Link]

  15. Xiufeng Li, Victor T. C. Tsang, Lei Kang, Yan Zhang, and Terence T. W. Wong, "High-speed high-resolution laser diode-based photoacoustic microscopy for in vivo microvasculature imaging," Vis. Comput. Ind. Biomed. Art 4, 1 (2021) [Link]

  16. Victor T. C. Tsang, Xiufeng Li, and Terence T. W. Wong, "A review of endogenous and exogenous contrast agents used in photoacoustic tomography with different sensing configurations," Sensors 20(19), 5595 (2020) (Invited review) [Link]

  17. Xiufeng Li, Lei Kang, Yan Zhang, and Terence T. W. Wong, "High-speed label-free ultraviolet photoacoustic microscopy for histology-like imaging of unprocessed biological tissues," Opt. Lett. 45(19), 5401–5404 (2020) [Link]

  18. Yang Li, Terence T. W. Wong, Junhui Shi, Hsun-Chia Hsu, and Lihong V. Wang, "Multifocal photoacoustic microscopy using a single-element ultrasonic transducer through an ergodic relay," Light Sci Appl 9, 135 (2020) [Link]

  19. Yu Lu, Terence T. W. Wong, Feng Chen, and Lidai Wang, “Compressed ultrafast spectral-temporal photography,” Phys. Rev. Lett. 122, 193904 (2019) [Link]
          *also selected as a highlighted article in Physical Review Letters, and featured by Physics [Details]

  20. Junhui Shi, Terence T. W. Wong, Yun He, Lei Li, Ruiying Zhang, Christopher S. Yung, Jeeseong Hwang, Konstantin Maslov, and Lihong V. Wang, “High-resolution, high-contrast mid-infrared imaging of fresh biological samples with ultraviolet-localized photoacoustic microscopy,” Nat. Photonics 13, 609–615 (2019) [Link]
          *featured by Phys.org [Details] and Optics.org [Details]​

  21. De Cai*, Terence T. W. Wong*, Liren Zhu, Junhui Shi, Sung-Liang Chen, and Lihong V. Wang, “Dual-view photoacoustic microscopy for quantitative cell nuclear imaging,” Opt. Lett. 43(20), 4875–4878 (2018) [Link] (*The authors contributed equally to the work)

    Before HKUST

  22. Hsun-Chia Hsu, Lei Li, Junjie Yao, Terence T. W. Wong, Junhui Shi, Konstantin Maslov, and Lihong V. Wang, “Dual-axis illumination for virtually augmenting the detection view of optical-resolution photoacoustic microscopy,” J. Biomed. Opt. 23(7), 076001 (2018) [Link]

  23. Yuan Qu, Lei Li, Yuecheng Shen, Xiaoming Wei, Terence T. W. Wong, Peng Hu, Junjie Yao, Konstantin Maslov, and Lihong V. Wang, “Dichroism-sensitive photoacoustic computed tomography,” Optica 5(4), 495-501 (2018) [Link]

  24. Toru Imai, Junhui Shi, Terence T. W. Wong, Lei Li, Liren Zhu, and Lihong V. Wang, “High-throughput ultraviolet photoacoustic microscopy with multifocal excitation,” J. Biomed. Opt. 23(3), 036007 (2018) [Link]

  25. Xiaowei Liu*, Terence T. W. Wong*, Junhui Shi, Jun Ma, and Lihong V. Wang, “Label-free cell nuclear imaging by Grüneisen relaxation photoacoustic microscopy,” Opt. Lett. 43(4), 947-950 (2018) [Link] (*The authors contributed equally to the work)

  26. Yan Liu, Yuecheng Shen, Haowen Ruan, Frank Bordie, Terence T. W. Wong, Changhuei Yang, and Lihong V. Wang, “Time-reversed ultrasonically encoded optical focusing through highly scattering ex vivo human cataractous lenses,” J. Biomed. Opt. 23(1), 010501 (2018) [Link]

  27. Terence T. W. Wong, Ruiying Zhang, Chi Zhang, Hsun-Chia Hsu, Konstantin Maslov, Lidai Wang, Junhui Shi, Ruimin Chen, K. Kirk Shung, Qifa Zhou, and Lihong V. Wang, “Label-free automated three-dimensional imaging of whole organs by microtomy-assisted photoacoustic microscopy,” Nat. Commun. 8, 1386 (2017) [Link]
          *also selected by Nature Communications to be indexed by Nature Index

  28. Terence T. W. Wong, Ruiying Zhang, Pengfei Hai, Chi Zhang, Miguel A. Pleitez, Rebecca L. Aft, Deborah V. Novack, and Lihong V. Wang, “Fast label-free multi-layered histology-like imaging of human breast cancer by photoacoustic microscopy,” Sci. Adv. 3, e1602168 (2017) [Link]
          *also selected as the cover rotator story in Science Advances
          *highly and widely publicized by Washington University in St. Louis (WUSTL), California Institute of Technology (Caltech), and public media worldwide [Details]

  29. Terence T. W. Wong, Yong Zhou, Alejandro Garcia-Uribe, Lei Li, Konstantin Maslov, Li Lin, Lihong V. Wang, "Use of a single xenon flash lamp for photoacoustic computed tomography of multiple-centimeter-thick biological tissue ex vivo and a whole mouse body in vivo," J. Biomed. Opt. 22(4), 041003 (2016) [Link]
          *featured by ElectroOptics and MedicalPhysics [Details]​​

  30. Junjie Yao, Lidai Wang, Joon-Mo Yang, Konstantin I. Maslov, Terence T. W. Wong, Lei Li, Chih-Hsien Huang, Jun Zou, and Lihong V. Wang, “High-speed label-free functional photoacoustic microscopy of mouse brain in action,” Nat. Methods 12(5), 407-410 (2015) [Link]
          *featured by Science [Details]

  31. Li Lin, Jun Xia, Terence T. W. Wong, Lei Li, and Lihong V. Wang, “In vivo deep brain imaging of rats using oral-cavity illuminated photoacoustic computed tomography,” J. Biomed. Opt. 20(1), 016019 (2015) [Link]

  32. Xiaoming Wei, Andy K. S. Lau, Terence T. W. Wong, Chi Zhang, Kevin K. Tsia, and Kenneth K. Y. Wong, “Coherent laser source for high frame-rate optical time-stretch microscopy at 1.0 μm,” IEEE J. Sel. Top. In Quant. Electron. 20(5), 1100306 (2014) [Link]

  33. Andy K. S. Lau, Terence T. W. Wong, Kenneth K. Y. Ho, Matthew T. H. Tang, Antony C. S. Chan, Edmund Y. Lam, Anderson H. C. Shum, Kenneth K. Y. Wong, and Kevin K. Tsia, “Interferometric time-stretch microscopy for ultrafast quantitative cellular and tissue imaging at 1 µm” J. Biomed. Opt. 19(7), 076001 (2014) [Link]

  34. Antony C. S. Chan, Terence T. W. Wong, Kenneth K. Y. Wong, Edmund Y. Lam, and Kevin K. Tsia, “Speed-dependent resolution analysis of ultrafast laser-scanning fluorescence microscopy,” J. Opt. Soc. Am. B 31(4), 755-764 (2014) [Link]
          *also selected for publication in Virtual Journal for Biomedical Optics, Vol 9, Iss. 6, (2014)

  35. Terence T. W. Wong, Andy K. S. Lau, Kenneth K. Y. Ho, Matthew T. H. Tang, Joseph D. F. Robles, Xiaoming Wei, Antony C. S. Chan, Anson H. L. Tang, Edmund Y. Lam, Kenneth K. Y. Wong, Godfrey C. F. Chan, H. C. Shum, and Kevin K. Tsia, “Asymmetric-detection time-stretch optical microscopy (ATOM) for ultrafast high-contrast cellular imaging in flow,” Sci. Rep. 4, 3656 (2014) [Link]
          *widely publicized by local media [Details]

  36. Terence T. W. Wong, Andy K. S. Lau, Kenneth K. Y. Wong, and Kevin K. Tsia, “Optical time-stretch confocal microscopy at 1 µm,” Opt. Lett. 37(16), 3330 (2012) [Link]
          *also selected for publication in Virtual Journal for Biomedical Optics, Vol 7, Iss. 10, (2012)

Conference Abstracts/Proceedings

​      @ HKUST

  1. Yan Zhang, Lei Kang, Wentao Yu, Victor T. C. Tsang, and Terence T. W. Wong, "Three-dimensional Histological Imaging Without Labels by Microtomy-assisted Autofluorescence Tomography," Biophotonics Congress: Biomedical Optics 2022, Fort Lauderdale, Florida, U.S.A, (April 2022)

  2. Ivy H. M. Wong, Yan Zhang, Lei Kang, Xiufeng Li, and Terence T. W. Wong, "Microscopy with Ultraviolet Surface Excitation using Speckle Illumination Enables High-throughput and Slide-free Histological Imaging," Biophotonics Congress: Biomedical Optics 2020, MTu1A.4 (Apr 2020)

  3. Yan Zhang, Lei Kang, Xiufeng Li, and Terence T. W. Wong, “High-throughput, label-free and slide-free histological imaging by ultraviolet-excited autofluorescence,” Biophotonics Congress: Biomedical Optics 2020, JW3A.24 (Apr 2020)

  4. Xiufeng Li, Lei Kang, Yan Zhang, and Terence T. W. Wong, "High-speed label-free galvo mirror scanning-based ultraviolet photoacoustic microscopy for histological imaging", Proc. SPIE 11240, Photons Plus Ultrasound: Imaging and Sensing 2020, 112401X (Feb 2020)

    Before HKUST

  5. Terence T. W. Wong, De Cai, Liren Zhu, Junhui Shi, Sung-Liang Chen, and Lihong V. Wang, “Quantitative cell nuclear imaging by dual-view optical-resolution photoacoustic microscopy,” SPIE Photonics West 2019 BiOS, San Francisco, California, U.S.A, (Feb 2019)

  6. Junhui Shi, Terence T. W. Wong, Yun He, Lei Li, Ruiying Zhang, Jeeseong Hwang, Konstantin Maslov, and Lihong V. Wang, “High-resolution high-contrast mid-infrared imaging of fresh biological samples with ultraviolet-localized photoacoustic microscopy,” SPIE Photonics West 2019 BiOS, San Francisco, California, U.S.A, (Feb 2019)

  7. Yang Li, Terence T. W. Wong, Junhui Shi, Hsun-Chia Hsu, and Lihong V. Wang, “Multifocal photoacoustic microscopy through an ergodic relay,” SPIE Photonics West 2019 BiOS, San Francisco, California, U.S.A, (Feb 2019)
    *2019 Seno Medical Best Paper Award with the most nominations: top 1 out of 242 papers

  8. Yan Liu, Yuecheng Shen, Haowen Ruan, Frank L. Brodie, Terence T. W. Wong, Changhuei Yang, and Lihong V. Wang, “Time-reversed ultrasonically encoded (TRUE) optical focusing through highly scattering ex vivo human cataractous lenses for congenital cataract treatment,” SPIE Photonics West 2019 BiOS, San Francisco, California, U.S.A, (Feb 2019)

  9. Terence T. W. Wong, Ruiying Zhang, Hsun-Chia Hsu, Konstantin Maslov, Junhui Shi, Ruimin Chen, K. Kirk Shung, Qifa Zhou, and Lihong V. Wang, “Whole-organ atlas imaged by label-free high-resolution photoacoustic microscopy assisted by a microtome,” SPIE Photonics West 2018 BiOS, San Francisco, California, U.S.A, (Feb 2018)
    *2018 Seno Medical Best Paper Award with the most nominations: top 1 out of 248 papers

  10. Terence T. W. Wong, Ruiying Zhang, Pengfei Hai, Rebecca L. Aft, Deborah V. Novack, and Lihong V. Wang, “Photoacoustic microscopy enables multilayered histological imaging of human breast cancer without staining,” SPIE Photonics West 2018 BiOS, San Francisco, California, U.S.A, (Feb 2018)

  11. Terence T. W. Wong, Xiaowei Liu, Junhui Shi, and Lihong V. Wang, “Photoacoustic microscopy for label-free optical sectioning cell nuclear imaging based on the Grüneisen relaxation effect,” SPIE Photonics West 2018 BiOS, San Francisco, California, U.S.A, (Feb 2018)

  12. Yuan Qu, Lei Li, Yuecheng Shen, Junjie Yao, Terence T. W. Wong, and Lihong V. Wang, “Imaging dichroism by photoacoustic computed tomography,” SPIE Photonics West 2018 BiOS, San Francisco, California, U.S.A, (Feb 2018)

  13. Terence T. W. Wong, Yong Zhou, Alejandro Garcia-Uribe, Lei Li, Konstantin Maslov, and Lihong V. Wang, “Photoacoustic tomography using a single xenon flash lamp,” SPIE Photonics West 2015 BiOS, San Francisco, California, U.S.A, (Feb 2015)

  14. Ruiying Zhang, Terence T. W. Wong, Chi Zhang, Konstantin Maslov, Lidai Wang, Ruimin Chen, Deborah V. Novack, Rebecca L. Aft, Qifa Zhou, and Lihong V. Wang, “Margin analysis of biological specimens with photoacoustic microscopy," SPIE Photonics West 2015 BiOS, San Francisco, California, U.S.A, (Feb 2015)

  15. Li Lin, Jun Xia, Terence T. W. Wong, Lei Li, and Lihong V. Wang, “Photoacoustic imaging with internal illumination,” SPIE Photonics West 2015 BiOS, San Francisco, California, U.S.A, (Feb 2015)

  16. Xiaoming Wei, Andy K. S. Lau, Terence T. W. Wong, Chi Zhang, Kevin K. Tsia, Kenneth K. Y. Wong, “Coherent laser source for optical time-stretched microscopy,” Conference on Lasers and Electro Optics/Quantum Electronics and Laser Science Conference (CLEO/QELC), San Jose, California, U.S.A, (June 2014)

  17. Antony C. S. Chan, Terence. T. W. Wong, Edmund Y. Lam, Kevin K. Tsia, “Revisit laser scanning fluorescence microscopy performance under fluorescence-lifetime-limited regime,” SPIE Photonics West 2014 BiOS, San Francisco, California, U.S.A, (Feb 2014)

  18. Terence T. W. Wong, Andy K. S. Lau, Matthew Y. H. Tang, Kenneth K. Y. Ho, Kenneth K. Y. Wong, Anderson H. C. Shum, Kevin K. Tsia, “Asymmetric-detection time-stretch optical microscopy (ATOM) for high-contrast and high-speed microfluidic cellular imaging,” SPIE Photonics West 2014 BiOS, San Francisco, California, U.S.A, (Feb 2014)

  19. Andy K. S. Lau, Terence T. W. Wong, Kenneth K. Y. Ho, Matthew Y. H. Tang, Joseph D. F. Robles, Xiaoming Wei, Antony C. S. Chan, Anson H. L. Tang, Edmund Y. Lam, Kenneth K. Y. Wong, Godfrey C. F. Chan, H. C. Shum, and Kevin K. Tsia, “Ultrafast high-contrast microfluidic cellular imaging by asymmetric-detection time-stretch optical microscopy (ATOM),” (Postdeadline paper) 2013 Frontiers in Optics/Laser Science XXIX (FiO/LS), in Orlando, Florida, (Oct 2013)

  20. Andy K. S. Lau, Terence T. W. Wong, Kenneth K. Y. Wong, Kevin K. Tsia, “Megahertz-scan-rate quantitative tissue imaging by interferometric time-stretch microscopy,” in Asia Communications and Photonics Conference (ACP), Beijing, China, (Dec 2013)

  21. Kevin K. Tsia, Kenneth K. Y. Wong, Andy K. S. Lau, Terence T. W. Wong, “Optical Time-Stretch Microscopy for ultrafast Optofluidic Imaging,” 7th International Conference on Nanophotonics/3rd Conference on Advances in Optoelectronics and Micro/Nano Optics (ICNP/AOM), Hong Kong, China, (May 2013)
    *INVITED

  22. Terence T. W. Wong, Matthew Y. H. Tang, Andy K. S. Lau, Antony C. S. Chan, Edmund Y. Lam, Kenneth K. Y. Wong, Anderson H. C. Shum, Kevin K. Tsia, “Ultrafast flow imaging by 1 µm time-stretch microscopy,” Novel Techniques in Microscopy (NTM), paper NW1B.5, Waikoloa Beach, Hawaii, USA, (Apr 2013)

  23. Andy K. S. Lau, Terence T. W. Wong, Antony C. S. Chan, Edmund Y. Lam, Kenneth K. Y. Wong, Kevin K. Tsia, “Interferometric time-stretch microscopy for ultrafast quantitative cellular imaging at 1 µm,” Novel Techniques in Microscopy (NTM), paper NW1B.4, Waikoloa Beach, Hawaii, USA, (Apr 2013)

  24. Terence T. W. Wong, Yi Qiu, Andy K. S. Lau, JingJiang Xu, Antony C. S. Chan, Kenneth K. Y. Wong, Kevin K. Tsia, “Cost effective approaches for high-resolution bioimaging by time-stretched confocal microscopy at 1µm,” Photonics Asia, paper 8853-65, Beijing, China, (Nov 2012)

  25. Terence T. W. Wong, Andy K. S. Lau, Kenneth K. Y. Wong, Kevin K. Tsia, “Cellular imaging by time-stretch confocal microscopy in the 1µm window,” Frontier in Optics/Laser Science XXVIII (FiO/LS) meeting, paper FTu1C.3, Rochester, New York, USA, (Oct 2012)

  26. Terence T. W. Wong, Antony C. S. Chan, Kenneth K. Y. Wong, Kevin K. Tsia, “Pixel super-resolution in serial time-encoded amplified microscopy (STEAM),” in Conference on Lasers and Electro Optics / Quantum Electronics and Laser Science Conference (CLEO/QELC), paper CTu3J.4, San Jose, California, USA, (May 2012)

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